ATTENTION! NEW Phase 2 regulations

• Only researchers approved for resuming research stage 1 or stage 2 can enter the Genomics Core and perform experiments in the Genomics Core.
• Two persons apart from the Core Director are allowed in the Genomics Core, but they cannot work in the same bay.
• Please indicate in the room calendar which instrument you will be using, e.g. qPCR or plate reader.

 All other rules from Phase 1 still apply.

Prior to reserving an instrument, please reserve the room in the Genomics Core Facility Room 109 calendar.  

Room Reservation Instructions: Genomics Core Facility Room 109

1. Open your Google Calendar through your Brown Gmail account.
2. Create an event by either:
     a. clicking the "Create" button on the top left of your calendar
     or
     b. clicking on the area in the calendar (Date and Time) that you want to reserve.
3. Add the event name and ensure the correct date and time.
4. Copy and paste the following Google Calendar ID into the "Add Guests" field.
Calendar ID: brown.edu_l2lvgrcv67t4ofkfbftrndldrk@group.calendar.google.com
5. Click the save button once you are finished. 

Requesting Full-Service Instruments

The Genomics core provides the following services.

• Next Generation Sequencing
• Affymetrix Microarray Service
• Quality Control of Nucleic Acids Analysis with Agilent Bioanalyzer and Fragment Analyzer
• NanoString - nCounter Sprint Profiler DNA & RNA Analysis
• Covaris S220 Focused-ultrasonicator*

For more information or to request service, please contact the facility director Christoph Schorl.

Reserving Self- Use Instruments

Internal users can click on the reservation button below to reserve the following instruments. For all other instruments and services, please contact the Facility Manager.

• ViiA 7 Real Time PCR Systems*
  • [A] 96 well block, TLDA block, 384-well block
  • [B] 96/TLDA block, 384-well block
• BIO-RAD QX200 Digital Droplet PCR
• Li-Cor Odyssey System
• Nanodrop One
• Cytation 5 Plate Readers
• Synergy H1 Hybrid Multi-Mode Reader
• Beckman Ultracentrifuge
• Countess Cell Counter
• Genepix Scanner

*Full or Self-Use available

External users may reserve equipment by contacting Christoph Schorl by email at Christoph_Schorl@brown.edu or by phone at (401) 863-2875.

Genomics Core Facility. This facility is located at the Laboratories of Molecular Medicine and staffed by a full-time PhD-level director. It provides investigators access to a variety of advanced instrumentation and training. DNA sequencing services are provided using an Illumina NextSeq 550 Sequencing System. Instrumentation housed in the facility includes a Nanostring nCounter® SPRINT™ Profiler, an Affymetrix Gene Chip Workstation, two ABI ViiA™ 7 Real-Time PCR Systems, a BIO-RAD QX200 Droplet Digital PCR, an Advanced Analytical Fragment Analyzer, a Cytation 5 Plate Reader, a Synergy H1 Hybrid Multimode (H1MM) Microplate Reader, a Covaris S220 Ultra-Sonicator, an Agilent 2100 Bioanalyzer, a LI-COR Odyssey Infrared Imaging System, a Countess Cell Counter, an AXON GenePix 4000B Scanner, a Beckman Optima Max Ultracentrifuge, and a Nanodrop ND 1000.

Scientific reproducibility is enhanced through scientific rigor and transparency.  Scientific rigor is the strict application of the scientific method to ensure unbiased and well-controlled experimental design, methodology, analysis, interpretation, and reporting of results. The Genomics Core is committed to supporting research excellence by adopting the following practices of scientific rigor.

• Purchase and maintain a variety of high-quality instruments from established vendors such that the best instrument is available for any given research analysis.
• The equipment is overseen by highly trained Genomics experts and well maintained under service contracts or funds budgeted for annual preventive maintenance and repairs.
• The Genomics experts are available for experimental design consults or troubleshooting.
• All Genomics users are thoroughly trained by the expert staff, one on one,  and not granted access to the instruments until they are deemed to be suitably trained. 
• All newly trained users are also required to use the instruments during daytime hours to increase interaction with the expert staff members.

Rigor and Reproducibility