Our ultra-shielded 500 MHz spectrometer operates with a room-temperature TXI z-gradient probe with automatic tuning and matching capability. The instrument is controlled using Topspin 3.1.
Division of Biology and Medicine
BioMed Core Facilities
500 MHz Bruker Avance II
500 MHz Bruker Avance II
Methods Library
Chemical Exchange
Wang C, Rance M, Palmer AG III. "Mapping chemical exchange in proteins with MW > 50 kD." J Am. Chem. Soc. 2003 (125): p 8968-9. DOI: 10.1021/ja035139z
Kneller JM, Lu M, and Bracken C. "An effective method for the discrimination of motional anisotropy and chemical exchange". J. Am. Chem. Soc. 2002 (124): p 1852-3. DOI: 10.1021/ja017461k
Dynamics Models
Lipari G and Szabo A. "Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules. 1. Theory and range of validity". J. Am. Chem. Soc. 1982 (104): p 4546-4559. DOI: 10.1021/ja00381a009