Division of Biology and Medicine
BioMed Core Facilities

Overview

The SKYSCAN 1276 is a high performance, stand-alone, fast, desktop in vivo microCT with continuously variable magnification for scanning small laboratory animals (mice, rats, ...) and biological samples. An optional Large Animal Transport System (LATS) is available which enables the system to mount also large animals including rabbits.

SKYSCAN 1276

Specifications

  • X-ray source: Continuous variable peak energy from 20 till 100kV, < 5 micron spot size at 4 watt; 20W maximum power, air cooled sealed type.
  • 6-positions automatic filter changer for energy selection: no filter, Al 0.5mm, Al 1mm, Al 0.5mm + Cu 0.03mm, Cu 0.1mm and “low-dose” filter (beam shaper).
  • X-ray detector: 11 Megapixel (4032 x 2688) 14-bit cooled digital X-ray CCD camera with fiber-optic coupling to scintillator, with 1x1, 2x2, 4x4 and 8x8 binning modes.
  • Image pixel size can be continuously adjusted from 2.8 μm till 10μm (full camera format) or up to 80μm (8x8 binning). Low contrast spatial resolution: <5 μm (10%MTF).
  • Round and helical scanning trajectories with patented (licensed) exact reconstruction.
  • Scanning using continuous gantry rotation or step-and shoot protocol, 3.9 sec shortest scanning cycle.
  • Scanning diameter: 12 ... 80mm dependent on magnification.
  • Scanning length: more than 300mm by multiple, automatically connected scans, 25mm in one camera field of view or >250mm by a single spiral (helical) scan.
  • Embedded touch screen display for scanner operation.
  • Integrated physiological monitoring (breathing, movement detection, ECG) for gating and time-resolved 4D micro-tomography.
  • Reconstruction arrays: cross section format (isotropic grid): up to 4000 x 4000 for up to 40mm scanning diameter and up to 8000 x 8000 pixels for up to 80mm scanning diameter.
  • Standard GPU-accelerated and optional world's fastest InstaRecon® 3D reconstructions
  • Supplied with GLP (Good Laboratory Practice) software.
  • System dimensions: 954mm W x 940mm H x 1190mm L (1560mm L with open specimen chamber), 330kg
  • Radiation safety: < 1 microSv/h average during full scan in 10cm from the instrument surface.
  • Power 100-240V/50-60Hz/3A (excluding workstation), 18-25°C temperature, <85% humidity, no condensation, vibrations 0.1 … 100Hz <0.1mm

Reservations

Scheduling

The Morphology Group Google calendar is used by Brown University faculty, staff and students for scheduling events and shared equipment usage. Use this Google calendar to sign up for time in the two x-ray rooms: the C-arm room and the Keck Lab.

To subscribe to the Morphology Group calendar for the first time, you will need to create a Google account if you do not already have one. Click the add google calendar image below to subscribe.

Google Calendar

A read-only version of the Morphology Group calendar is also available.